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Tea waste rich with extractable antioxidants

 

02/12/2005- Tea waste is almost as rich in potent antioxidants, such as catechins, as the new and expensive green tea leaves used by the supplements industry, according to Iranian research to be published later this month in peer-reviewed journal Food Chemistry.

The study, carried out by the Ferdowsi University of Mashhad, investigated three extraction methods on different parts of the tea plant, and tea waste, and found surprisingly high levels of antioxidants across all of the extracts.
Tea leaves that have already matured on the plant and the waste that is left after fermenting black tea, “are often considered as agricultural wastes”, said Dr Reza Farhoosh, the author of the study. But they “could be used as potent natural antioxidative sources”. European demand for tea extracts is currently surging, having reached 500 metric tonnes by 2003. With tea prices at around $1.5 per kg, the possibility of cheaper raw materials could shift the industry’s cost base. Green tea and green tea extracts are currently produced from only the first two to four leaves of the tea plant (Camellia sinensis). The other leaves are known as old tea leaves (OTL). Fermenting the green tea leaves produces black tea, and obviously produces black tea waste (BTW). The Iranian study reported high extraction yields of polyphenols from OTL and BTW, including epigallocatechin gallate (EGCG), one of the most widely researched polyphenols in green tea. Three different extraction media were studied, using hot water, methanol or ethyl acetate. For both green tea and black tea waste, the most efficient of the three methods was hot water extraction, which delivered yields of 35 per cent for fresh green tea leaves and a close-running 30 per cent for BTW. Extracts from green tea are now well established as sources of polyphenols – containing a rich source of free radical scavenging catechins. Recent data suggests these compounds play a beneficial role in weight loss, cardiovascular and oral health, with some now emerging as particularly powerful.

 

Silicon may boost calcium/vitamin D bone benefits

 

23/11/2005- New research adds to mounting evidence that silicon delivered as choline-stabilised orthosilicic acid (ch-OSAT) may boost the ability of calcium and vitamin D to build bone mineral density (BMD) in osteoporosis and osteopenia sufferers.

The latest study, led by Professor Tim Spector of St Thomas Hospital in London, UK, builds on an earlier investigation indicating that the benefits of ch-OSA in helping build and maintain bone lie in its regulation of bone mineralization, which help trigger the deposition of calcium and phosphate, reducing the number of bone-destroying cells (called osteoclasts) and increasing the number of bone-building cells (osteoblasts).  Spector and his team divided a group of 114 women, all of whom suffered from osteoporosis or osteopenia (bones that are less dense than normal, giving the individual a higher risk of developing osteoporosis), into four groups.  Over a 12-month period the placebo group received the standard recommended dose of calcium and vitamin D3 for osteopenia and mild osteoporosis each day – that is, 1000mg and 800IU respectively.  The other three groups received the same calcium and vitamin D3 doses, but in addition from Jarrow Formulas).  The researchers measured the benefit of the ch-OSA through markers of bone formation, such as Procollagen Type I N-terminal Propeptide (PINP), Bone Specific Alkaline Phosphatase (BAP) and Osteocalcin. Their findings were presented at the weekend at the conference of the American Society of Bone and Mineral Research in Nashville, Tennessee. Overall, they noted that the ch-OSA seemed to confer some additional benefit to Ca/Vit D3 supplementation. The effect was particularly pronounced in the PINP, the most sensitive bone formation marker. In the groups receiving six and 12mg of silicon, the improvements were “significant”. Interestingly, there appeared to be no significant effect on spinal BMD, but significant changes in femoral BMD were noted in a subgroup of women with a low femur T-score at the start of the study. This finding was consistent with earlier animal studies.
"This study suggests that combined therapy of ch-OSA plus Ca/Vit D3 is a safe, well tolerated treatment that has a potentially beneficial effect on bone turnover, especially bone collagen, and possibly femoral BMD, compared to Ca/Vit D3 alone," concluded the researchers. The study was supported by a grant from the UK’s National Osteoporosis Society. A spokeswoman for the charity said: “We are especially interested in this work as it demonstrates potential benefits to people with osteoporosis.

 

Korean research touts fermented cabbage as a possible cure
 

By KAREN HERZOG
 

kherzog@journalsentinel.com
 

Posted: Nov. 3, 2005
  While President Bush scrambles to ward off an avian flu pandemic, the world's largest sauerkraut producer, tucked amid the glacial lakebeds of rural Wisconsin, is sitting atop a bumper crop of one possible preventative.   That's right: Sauerkraut.   An international buzz is surrounding the unassuming, fermented cruciferous vegetable that costs 89 cents per 14.5-ounce can. Scientists at Seoul National University in South Korea fed an extract of kimchi, a spicy Korean variant of sauerkraut, to 13 chickens infected with avian flu, and a week later, 11 of the birds started to recover, according to a report by the BBC Network.  In case everyone is going out to buy sauerkraut, I want to point out that most commercial sauerkraut is HEATED to pasteurize the product and presumably make it salfe. But this sterilization process kills all the beneficial bacteria.  The kimchee used in the promising study was not heated. Real kimchee is not cooked or heated. It is made with raw cabbage and then fermented. Also, real kimchee has lots of cayenne and garlic in it. So yes, sauerkraut is a miracle food in a lot of ways. But if you buy it, make sure it's raw and not pasteurized. The only place you can buy sauerkraut like this is in a health food store. And even there, you have to read the labels to make sure it's raw.

 

B vitamins to lower homocysteine may prevent strokes

 

10/11/2005- Taking high doses of B vitamins may help reduce the risk of a second stroke and heart attacks, according to a new analysis.

The B vitamin group, including folic acid, B6, and B12, reduce the amount of the amino acid homocysteine in the blood. High levels of this substance have been linked to heart disease. But a previous study by the Vitamin Intervention for Stroke Prevention (VISP) group based in Canada and the US suggested that taking a combination of B9, B6 and B12 did not reduce recurrent stroke and cardiac events. However work carried out since then suggested to the team that their initial trial included patients who were not likely to benefit from the treatment.  In a new analysis they excluded patients with low and very high B12 levels at baseline. These were likely to have B12 malabsorption or to be taking B12 supplements outside the study. Patients with significant renal impairment were also excluded as they were unlikely to respond to vitamin therapy. In the remaining 2155 patients, high-dose vitamin supplements reduced recurrent stroke, death and heart disease by 21 per cent compared with those taking low-dose vitamins, they report in the 1 November issue of Stroke Stroke (vol 36, p2404). When they subdivided patients by baseline levels of vitamin B12, thus identifying those with difficulties absorbing the vitamin, the differences between the low-dose and high-dose groups became greater. The authors suggest that given the fortification of flour with folate, the response to vitamin therapy for lowering homocysteine largely depends on B12 levels of heart patients. Higher doses of B12 could be required to reduce homocysteine, and thus to reduce stroke and heart attack.

 

Aloe vera developed as natural preservative

 

23/09/2005- Researchers in Spain have developed an aloe vera gel that can be used as an edible coating to prolong the quality and safety of fresh produce.

The gel, which scientists claim does not appear to affect food taste or appearance, could soon provide a safe, natural and environmentally-friendly alternative to conventional synthetic preservatives that are currently applied to produce after harvesting.

Daniel Valero, Ph.D., of the University of Miguel Hernández in Alicante, Spain and his associates dipped a group of common table grapes (Crimson Seedless) into Aloe vera gel and stored them for five weeks under low temperature while exposing a group of untreated table grapes to the same conditions.  The colourless Aloe gel used in this study was developed through a special processing technique that maximised the amount of active compounds in the gel.  The untreated grapes appeared to deteriorate rapidly within about seven days, whereas the gel-coated grapes were well-preserved for up to 35 days under the same experimental conditions. The gel-treated grapes were firmer, had less weight loss and less colour change than the untreated grapes, measures which correspond to higher freshness. A sensory panel of 10 people evaluated the quality of both the untreated and the gel-treated grapes by consuming some of the grapes. They found that the gel-treated grapes were generally superior in taste. Although a number of edible coatings have been developed to preserve food freshness, the new coating is believed to be the first to use Aloe vera.  The researchers believe that the gel works through a combination of mechanisms. Composed mostly of polysaccharides, the gel appears to act as a natural barrier to moisture and oxygen, which can speed food deterioration.  But the gel also enhances food safety. Based on previous studies by others, Aloe vera gel appears to contain various antibiotic and antifungal compounds that can potentially delay or inhibit microorganisms that are responsible for foodborne illness in humans as well as food spoilage.  Although the health effects of Aloe gel on human consumption were not directly measured in this study, the scientists are confident that coating is safe. They note that Aloe vera gel has been used as a functional ingredient in some foods and beverages for years. In addition to preserving table grapes, which are highly perishable, the gel can be applied to other fruits and vegetables. Further testing of the gel on other types of produce is anticipated. The gel also offers potential environmental benefits. It could provide a greener alternative to sulphur dioxide and other synthetic food preservatives that are commonly used on produce and increasingly the target of health concerns. Valero and his associates have now filed a patent application in Spain for their gel. His findings will appear in the 5 October print issue of the American Chemical Society’s Journal of Agricultural and Food Chemistry, the Society’s peer-reviewed publication.  Funding for this study was provided by the Spanish Ministry of Science and Technology and the European Commission via FEDER (European fund for regional development).

 

Red wine improves artery health in heart patients

 

20/10/2005- Antioxidants in red wine appear to have positive effects on the arteries of people with heart disease, according to a Greek study.


A team from Harokopio University in Athens found that both red wine, and wine that had the alcohol removed, reduced artery stiffness in 15 subjects with coronary artery disease. This condition - defined stiff arteries - raises blood pressure and puts patients at risk for heart attack. Because the effects were observed with non-alcoholic wine, the researchers attributed these effects to antioxidants in the red wine. The double-blind, cross-over study, reported in the September issue of the American Journal of Hypertension (vol 18, issue 9, pp1161-7), also showed that after consuming either 250ml of regular or dealcoholized red wine, patients saw a significant decrease in central systolic blood pressure, the top reading of the blood pressure. Central systolic blood pressure fell 7.4 mm Hg and 5.4 mm Hg after consumption of red wine and non-alcoholic red wine, respectively. The mechanisms for the reduction of arterial stiffness are not well understood

 

Olive oil phenols may explain heart health benefits

 

10/11/2005- Plant chemicals in olive oil, rather than the fatty acids, may be responsible for the good heart health widely observed in Mediterranean populations, say Spanish researchers.

In a study on blood vessel function in human volunteers, they found that a polyphenol-rich olive oil caused a significant improvement but there was little effect after subjects consumed an oil that had many of the phenols removed. Healthy blood vessels ensure proper blood flow around the body whereas unhealthy vessels can eventually lead to blockages with implications for the heart.
The work by a team from the Reina Sofia University Hospital in Córdoba is one of a growing number of investigations going on around the world to better understand why olive oil protects the heart. Several epidemiological studies have linked high consumption of olive oil, a key ingredient in the traditional Mediterranean diet, to lower incidence of heart disease in many south European countries. But only in recent years have researchers begun to investigate how the plant oil exerts these beneficial effects. Identifying a mechanism for a food’s health effect is key to confirming its healthy properties and gaining scientific credibility for its consumption as a health food. The work on olive oil is complex however as it contains hundreds of potentially active compounds, many of which are not well-known. Moreover with numerous varieties of oil available, studies cannot be easily compared. Yet there have been some recent breakthroughs. In September, US scientists identified a previously unknown chemical, which they called oleocanthal, that has a strong anti-inflammatory action.

They compared its action on COX enzymes to that of drugs like the common painkiller ibuprofen.

The new research, to be published in the 15 November issue of the Journal of the American College of Cardiology (vol 46, pp 1864-1868), is also important as it is the first to show a direct benefit of an olive oil with high content in phenolic compounds on endothelial function in humans, according to the authors. Phenols are a large group of compounds that include flavonoids such as anthocyanins and quercetin, phenolic acids like ellagic acid, fibres such as lignans and vitamins. Many of these have antioxidant, anti-inflammatory and anti-clotting properties, all of which are known to benefit cardiovascular health. The Spanish scientists looked particularly at the response of the endothelium, or inner lining, of small blood vessels in the fingers of subjects to sudden changes in blood flow, which were produced by inflating and then deflating a blood pressure cuff. Poor responsiveness to this sort of blood flow test is considered an early warning sign of cardiovascular disease. Previous studies have linked high-fat meals to poor endothelial function lasting for several hours after eating. So the team designed a study on a relatively high-fat meal - 60g of white bread with 40ml of olive oil. The subjects, 21 adults with high cholesterol levels, were randomized to receive either an olive oil high in phenolic compounds (400 parts per million) or the same brand of oil that had been processed to remove most of the phenolic compounds (80 parts per million remaining). Then they crossed over and repeated the study to consume the other oil. Consumption of the polyphenol-rich breakfast was associated with an improvement in endothelial function, as well as a greater increase in concentrations of nitric oxide, report the researchers. "Virgin olive oil is more than fat because it is a real juice with other healthy micronutrients," said author author Dr Francisco Pérez Jiménez.  "We think, looking at our results, that the reduction in oxidative stress and the increase in the nitric oxide bioavailability are behind the observed improvement in ischaemic reactive hyperemia," he said.  But he cautioned that further studies in "appropriate populations, or with a large sample size, are required to definitively establish the in vivo antioxidant properties of these components in relation to cardiovascular disease outcomes."

Moreover, the scientist noted that not all olive oils have a high phenolic content. But the results add up to the evidence to support increasing consumption of olive oil as way of preventing progression of atherosclerosis.

 

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